Growth Inhibition and Apoptosis Due to Restoration of E2A Activity in T Cell Acute Lymphoblastic Leukemia Cells

Two models have been proposed for the molecular mechanism by which the Tal1 oncogene causes T cell acute lymphoblastic leukemia (T-ALL). The activation model suggests that Tal1 as heterodimers with the E2A transcription factor activates the expression of oncogenes. The inhibition model postulates th...

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Detalles Bibliográficos
Autores principales: Park, Steven T., Nolan, Garry P., Sun, Xiao-Hong
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192921/
https://www.ncbi.nlm.nih.gov/pubmed/9927512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192921/
https://www.ncbi.nlm.nih.gov/pubmed/9927512

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