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Interferons Regulate the Phenotype of  Wild-type and Mutant Herpes Simplex Viruses In Vivo

Mechanisms responsible for neuroattenuation of herpes simplex virus (HSV) have been defined previously by studies of mutant viruses in cultured cells. The hypothesis that null mutations in host genes can override the attenuated phenotype of null mutations in certain viral genes was tested. Mutants s...

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Detalles Bibliográficos
Autores principales: Leib, David A., Harrison, Travis E., Laslo, Kathleen M., Machalek, Michael A., Moorman, Nathaniel J., Virgin, Herbert W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192939/
https://www.ncbi.nlm.nih.gov/pubmed/9989981