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Cytotoxicity Is Mandatory for CD8(+) T Cell–mediated Contact Hypersensitivity

Contact hypersensitivity (CHS) is a T cell–mediated skin inflammation induced by epicutaneous exposure to haptens in sensitized individuals. We have previously reported that CHS to dinitrofluorobenzene in mice is mediated by major histocompatibility complex (MHC) class I–restricted CD8(+) T cells. I...

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Detalles Bibliográficos
Autores principales: Kehren, Jeanne, Desvignes, Cyril, Krasteva, Maya, Ducluzeau, Marie-Thérèse, Assossou, Olga, Horand, Françoise, Hahne, Michael, Kägi, David, Kaiserlian, Dominique, Nicolas, Jean-François
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192953/
https://www.ncbi.nlm.nih.gov/pubmed/10049941