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An Invariant T Cell Receptor α Chain Defines a Novel TAP-independent Major Histocompatibility Complex Class Ib–restricted α/β T Cell Subpopulation in Mammals

We describe here a new subset of T cells, found in humans, mice, and cattle. These cells bear a canonical T cell receptor (TCR) α chain containing hAV7S2 and AJ33 in humans and the homologous AV19-AJ33 in mice and cattle with a CDR3 of constant length. These T cells are CD4(−)CD8(−) double-negative...

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Detalles Bibliográficos
Autores principales: Tilloy, Florence, Treiner, Emmanuel, Park, Se-Ho, Garcia, Corinne, Lemonnier, François, de la Salle, Henri, Bendelac, Albert, Bonneville, Marc, Lantz, Olivier
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192962/
https://www.ncbi.nlm.nih.gov/pubmed/10377186