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Lipoxin (LX)A(4) and Aspirin-triggered 15-epi-LXA(4) Inhibit Tumor Necrosis Factor 1α–initiated Neutrophil Responses and Trafficking: Regulators of a Cytokine–Chemokine Axis

The impact of  lipoxin A(4) (LXA(4)) and aspirin-triggered lipoxins (ATLs) was investigated in tumor necrosis factor (TNF)-α–initiated neutrophil (polymorphonuclear leukocyte) responses in vitro and in vivo using metabolically stable LX analogues. At concentrations as low as 1–10 nM, the LXA(4) and...

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Detalles Bibliográficos
Autores principales: Hachicha, Mohamed, Pouliot, Marc, Petasis, Nicos A., Serhan, Charles N.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192964/
https://www.ncbi.nlm.nih.gov/pubmed/10377187