B7-1 or B7-2 Is Required to Produce the Lymphoproliferative Phenotype in Mice Lacking Cytotoxic T Lymphocyte–associated Antigen 4 (CTLA-4)

The costimulatory molecules B7-1 and B7-2 regulate T lymphocyte activation by delivering activating signals through CD28 and inhibitory signals through cytotoxic T lymphocyte–associated antigen 4 (CTLA-4). The importance of CTLA-4–mediated inhibition was demonstrated by the uncontrolled T cell activ...

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Detalles Bibliográficos
Autores principales: Mandelbrot, Didier A., McAdam, Alexander J., Sharpe, Arlene H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Brief Definitive Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192978/
https://www.ncbi.nlm.nih.gov/pubmed/9892625

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192978/
https://www.ncbi.nlm.nih.gov/pubmed/9892625

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