Initiation of Autoimmune Diabetes by Developmentally Regulated Presentation of Islet Cell Antigens in the Pancreatic Lymph Nodes

Little is known about the events triggering lymphocyte invasion of the pancreatic islets in prelude to autoimmune diabetes. For example, where islet-reactive T cells first encounter antigen has not been identified. We addressed this issue using BDC2.5 T cell receptor transgenic mice, which express a...

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Detalles Bibliográficos
Autores principales: Höglund, Petter, Mintern, Justine, Waltzinger, Caroline, Heath, William, Benoist, Christophe, Mathis, Diane
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192987/
https://www.ncbi.nlm.nih.gov/pubmed/9892615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192987/
https://www.ncbi.nlm.nih.gov/pubmed/9892615

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