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Positive and Negative Regulation of  V(D)J Recombination by the E2A Proteins

A key feature of B and T lymphocyte development is the generation of antigen receptors through the rearrangement and assembly of the germline variable (V), diversity (D), and joining (J) gene segments. However, the mechanisms responsible for regulating developmentally ordered gene rearrangements are...

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Detalles Bibliográficos
Autores principales: Bain, Gretchen, Romanow, William J., Albers, Karen, Havran, Wendy L., Murre, Cornelis
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192990/
https://www.ncbi.nlm.nih.gov/pubmed/9892611