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The Effect of Graft-versus-Host Disease on T Cell Production and Homeostasis

The aim of this work was to decipher how graft-versus-host disease (GVHD) affects T cell production and homeostasis. In GVHD(+) mice, thymic output was decreased fourfold relative to normal mice, but was sufficient to maintain a T cell repertoire with normal diversity in terms of Vβ usage. Lymphoid...

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Detalles Bibliográficos
Autores principales: Dulude, Gaël, Roy, Denis-Claude, Perreault, Claude
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193018/
https://www.ncbi.nlm.nih.gov/pubmed/10209049