Regulation of Interleukin (IL)-12 Receptor β2 Subunit Expression by Endogenous IL-12: A Critical Step in the Differentiation of Pathogenic Autoreactive T Cells

The interleukin (IL)-12 receptor (R)β2 subunit is the critical molecule involved in maintaining IL-12 responsiveness and controlling T helper cell type 1 lineage commitment. We demonstrate that IL-12 and interferon (IFN)-γ play separate, but complementary, roles in regulating IL-12Rβ2 expression on...

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Detalles Bibliográficos
Autores principales: Chang, John T., Shevach, Ethan M., Segal, Benjamin M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193042/
https://www.ncbi.nlm.nih.gov/pubmed/10075980

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193042/
https://www.ncbi.nlm.nih.gov/pubmed/10075980

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