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Recognition of the Major Histocompatibility Complex Restriction Element Modulates CD8(+) T Cell Specificity and Compensates for Loss of T Cell Receptor Contacts with the Specific Peptide
Triggering of a T cell requires interaction between its specific receptor (TCR) and a peptide antigen presented by a self–major histocompatibility complex (MHC) molecule. TCR recognition of self-MHC by itself falls below the threshold of detection in most systems due to low affinity. To study this i...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1999
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193044/ https://www.ncbi.nlm.nih.gov/pubmed/10075972 |