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Inhibition of  T Cell Proliferation by Macrophage Tryptophan Catabolism

We have recently shown that expression of the enzyme indoleamine 2,3-dioxygenase (IDO) during murine pregnancy is required to prevent rejection of the allogeneic fetus by maternal T cells. In addition to their role in pregnancy, IDO-expressing cells are widely distributed in primary and secondary ly...

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Detalles Bibliográficos
Autores principales: Munn, David H., Shafizadeh, Ebrahim, Attwood, John T., Bondarev, Igor, Pashine, Achal, Mellor, Andrew L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193062/
https://www.ncbi.nlm.nih.gov/pubmed/10224276