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Expression of the c-myc Proto-oncogene Is Essential for HIV-1 Infection in Activated T Cells

We previously found that activation of primary CD4(+) T cells via both the T cell antigen receptor (TCR) and CD28 is required for HIV-1 DNA to be translocated from the cytoplasm to the nucleus. Here we report that expression of c-Myc protein in CD4(+) T cells is induced only after such costimulation...

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Detalles Bibliográficos
Autores principales: Sun, Yu, Clark, Edward A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193066/
https://www.ncbi.nlm.nih.gov/pubmed/10224279