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Expression of the c-myc Proto-oncogene Is Essential for HIV-1 Infection in Activated T Cells
We previously found that activation of primary CD4(+) T cells via both the T cell antigen receptor (TCR) and CD28 is required for HIV-1 DNA to be translocated from the cytoplasm to the nucleus. Here we report that expression of c-Myc protein in CD4(+) T cells is induced only after such costimulation...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1999
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193066/ https://www.ncbi.nlm.nih.gov/pubmed/10224279 |