pH-dependent Peptide Binding Properties of the Type I Diabetes–associated I-A(g7) Molecule: Rapid Release of CLIP at an Endosomal pH

MHC class II molecules and invariant chain assemble at a neutral pH in the endoplasmic reticulum and are transported to a low pH compartment where the invariant chain is trimmed to the class II–associated invariant chain peptide (CLIP). For many major histocompatibility complex class II molecules, D...

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Detalles Bibliográficos
Autores principales: Hausmann, Dorothee H.F., Yu, Bei, Hausmann, Stefan, Wucherpfennig, Kai W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193072/
https://www.ncbi.nlm.nih.gov/pubmed/10359576

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193072/
https://www.ncbi.nlm.nih.gov/pubmed/10359576

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