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pH-dependent Peptide Binding Properties of the Type I Diabetes–associated I-A(g7) Molecule: Rapid Release of CLIP at an Endosomal pH
MHC class II molecules and invariant chain assemble at a neutral pH in the endoplasmic reticulum and are transported to a low pH compartment where the invariant chain is trimmed to the class II–associated invariant chain peptide (CLIP). For many major histocompatibility complex class II molecules, D...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1999
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193072/ https://www.ncbi.nlm.nih.gov/pubmed/10359576 |