Severe B Cell Deficiency in Mice Lacking the Tec Kinase Family Members Tec and Btk

The cytoplasmic protein tyrosine kinase Tec has been proposed to have important functions in hematopoiesis and lymphocyte signal transduction. Here we show that Tec-deficient mice developed normally and had no major phenotypic alterations of the immune system. To reveal potential compensatory roles...

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Detalles Bibliográficos
Autores principales: Ellmeier, Wilfried, Jung, Steffen, Sunshine, Mary Jean, Hatam, Farah, Xu, Yang, Baltimore, David, Mano, Hiroyuki, Littman, Dan R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193106/
https://www.ncbi.nlm.nih.gov/pubmed/11104803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193106/
https://www.ncbi.nlm.nih.gov/pubmed/11104803

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