Cargando…
Severe B Cell Deficiency in Mice Lacking the Tec Kinase Family Members Tec and Btk
The cytoplasmic protein tyrosine kinase Tec has been proposed to have important functions in hematopoiesis and lymphocyte signal transduction. Here we show that Tec-deficient mice developed normally and had no major phenotypic alterations of the immune system. To reveal potential compensatory roles...
Autores principales: | Ellmeier, Wilfried, Jung, Steffen, Sunshine, Mary Jean, Hatam, Farah, Xu, Yang, Baltimore, David, Mano, Hiroyuki, Littman, Dan R. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2000
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193106/ https://www.ncbi.nlm.nih.gov/pubmed/11104803 |
Ejemplares similares
-
A Tec kinase BTK inhibitor ibrutinib promotes maturation and activation of dendritic cells
por: Natarajan, Gayathri, et al.
Publicado: (2016) -
The Non-receptor Tyrosine Kinase Tec Controls Assembly and Activity of the Noncanonical Caspase-8 Inflammasome
por: Zwolanek, Florian, et al.
Publicado: (2014) -
Chemical degradation of BTK/TEC as a novel approach to inhibit platelet function
por: Trory, Justin S., et al.
Publicado: (2022) -
TEC Installation
por: CERN. Geneva. Audiovisual Unit
Publicado: (1989) -
The Tyrosine Kinase Tec Regulates Effector Th17 Differentiation, Pathogenicity, and Plasticity in T-Cell-Driven Intestinal Inflammation
por: Sandner, Lisa, et al.
Publicado: (2021)