Multiple Genetic Alterations Cause Frequent and Heterogeneous Human Histocompatibility Leukocyte Antigen Class I Loss in Cervical Cancer

The nature and frequency of human histocompatibility leukocyte antigen (HLA) class I loss mechanisms in primary cancers are largely unknown. We used flow cytometry and molecular analyses to concurrently assess allele-specific HLA phenotypes and genotypes in subpopulations from 30 freshly isolated ce...

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Detalles Bibliográficos
Autores principales: Koopman, Louise A., Corver, Willem E., van der Slik, Arno R., Giphart, Marius J., Fleuren, Gert Jan
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193119/
https://www.ncbi.nlm.nih.gov/pubmed/10727458

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193119/
https://www.ncbi.nlm.nih.gov/pubmed/10727458

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