Role of 2c T Cell Receptor Residues in the Binding of Self–And Allo–Major Histocompatibility Complexes

T cell clone 2C recognizes the alloantigen L(d) and the positive selecting major histocompatibility complex (MHC), K(b). To explore the molecular basis of T cell antigen receptor (TCR) binding to different peptide/MHC (pMHC) complexes, we performed alanine scanning mutagenesis of the 2C TCR. The TCR...

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Detalles Bibliográficos
Autores principales: Lee, Peter U.Y., Churchill, Hywyn R.O., Daniels, Mark, Jameson, Stephen C., Kranz, David M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193126/
https://www.ncbi.nlm.nih.gov/pubmed/10770802

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193126/
https://www.ncbi.nlm.nih.gov/pubmed/10770802

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