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Evidence for Class-Specific Factors in Immunoglobulin Isotype Switching

Immunoglobulin class switch recombination (SR) occurs by a B cell–specific, intrachromosomal deletional process between switch regions. We have developed a plasmid-based transient transfection assay for SR to test for the presence of transacting switch activities. The plasmids are novel in that they...

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Detalles Bibliográficos
Autores principales: Shanmugam, Ananth, Shi, Meng-Jiao, Yauch, Lauren, Stavnezer, Janet, Kenter, Amy L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193137/
https://www.ncbi.nlm.nih.gov/pubmed/10770803