Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand (Trail) Is an Inhibitor of Autoimmune Inflammation and Cell Cycle Progression

The tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) induces apoptosis of tumor cells but not normal cells; its role in normal nontransformed tissues is unknown. We report here that chronic blockade of TRAIL in mice exacerbated autoimmune arthritis, and that intraarticular TRAIL gene...

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Detalles Bibliográficos
Autores principales: Song, Kaimei, Chen, Yiguang, Göke, Rüdiger, Wilmen, Andreas, Seidel, Cheryl, Göke, Alexandra, Hilliard, Brendan, Chen, Youhai
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193179/
https://www.ncbi.nlm.nih.gov/pubmed/10748228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193179/
https://www.ncbi.nlm.nih.gov/pubmed/10748228

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