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Hematopoietic Expression of Hoxb4 Is Regulated in Normal and Leukemic Stem Cells through Transcriptional Activation of the Hoxb4 Promoter by Upstream Stimulating Factor (Usf)-1 and Usf-2

The homeobox genes encode a family of transcription factors that regulate development and postnatal tissue homeostasis. Since HOXB4 plays a key role in regulating the balance between hematopoietic stem cell renewal and differentiation, we studied the molecular regulation of HOXB4 expression in human...

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Detalles Bibliográficos
Autores principales: Giannola, Diane M., Shlomchik, Warren D., Jegathesan, Mithila, Liebowitz, David, Abrams, Charles S., Kadesch, Tom, Dancis, Andrew, Emerson, Stephen G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193192/
https://www.ncbi.nlm.nih.gov/pubmed/11085749