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Immunization and Infection Change the Number of Recombination Activating Gene (Rag)-Expressing B Cells in the Periphery by Altering Immature Lymphocyte Production

Recombination activating gene (RAG) expression in peripheral B cells increases after immunization with (4-hydroxy-3-nitrophenyl) acetyl coupled to chicken gamma globulin (NP-CGG) in alum. This increase could result from reinduction of RAG expression or, alternatively, from accumulation of RAG-expres...

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Detalles Bibliográficos
Autores principales: Nagaoka, Hitoshi, Gonzalez-Aseguinolaza, Gloria, Tsuji, Moriya, Nussenzweig, Michel C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193199/
https://www.ncbi.nlm.nih.gov/pubmed/10859336