Mitochondrial Basis for Immune Deficiency: Evidence from Purine Nucleoside Phosphorylase–Deficient Mice

We generated purine nucleoside phosphorylase (PNP)-deficient mice to gain insight into the mechanism of immune deficiency disease associated with PNP deficiency in humans. Similar to the human disease, PNP deficiency in mice causes an immunodeficiency that affects T lymphocytes more severely than B...

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Detalles Bibliográficos
Autores principales: Arpaia, Enrico, Benveniste, Patricia, Di Cristofano, Antonio, Gu, Yiping, Dalal, Ilan, Kelly, Susan, Hershfield, Michael, Pandolfi, Pier Paolo, Roifman, Chaim M., Cohen, Amos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193200/
https://www.ncbi.nlm.nih.gov/pubmed/10859343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193200/
https://www.ncbi.nlm.nih.gov/pubmed/10859343

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