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The Structural Basis of Repertoire Shift in an Immune Response to Phosphocholine

The immune response to phosphocholine (PC)–protein is characterized by a shift in antibody repertoire as the response progresses. This change in expressed gene combinations is accompanied by a shift in fine specificity toward the carrier, resulting in high affinity to PC–protein. The somatically mut...

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Detalles Bibliográficos
Autores principales: Brown, McKay, Schumacher, Maria A., Wiens, Gregory D., Brennan, Richard G., Rittenberg, Marvin B.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193205/
https://www.ncbi.nlm.nih.gov/pubmed/10859335