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A Hierarchical Role for Classical Pathway Complement Proteins in the Clearance of Apoptotic Cells in Vivo

The strongest susceptibility genes for the development of systemic lupus erythematosus (SLE) in humans are null mutants of classical pathway complement proteins. There is a hierarchy of disease susceptibility and severity according to the position of the missing protein in the activation pathway, wi...

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Detalles Bibliográficos
Autores principales: Taylor, Philip R., Carugati, Anna, Fadok, Valerie A., Cook, H. Terence, Andrews, Mark, Carroll, Michael C., Savill, John S., Henson, Peter M., Botto, Marina, Walport, Mark J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193213/
https://www.ncbi.nlm.nih.gov/pubmed/10934224