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A Hierarchical Role for Classical Pathway Complement Proteins in the Clearance of Apoptotic Cells in Vivo
The strongest susceptibility genes for the development of systemic lupus erythematosus (SLE) in humans are null mutants of classical pathway complement proteins. There is a hierarchy of disease susceptibility and severity according to the position of the missing protein in the activation pathway, wi...
Autores principales: | Taylor, Philip R., Carugati, Anna, Fadok, Valerie A., Cook, H. Terence, Andrews, Mark, Carroll, Michael C., Savill, John S., Henson, Peter M., Botto, Marina, Walport, Mark J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193213/ https://www.ncbi.nlm.nih.gov/pubmed/10934224 |
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