Signal Transduction by Cxc Chemokine Receptor 4: Stromal Cell–Derived Factor 1 Stimulates Prolonged Protein Kinase B and Extracellular Signal–Regulated Kinase 2 Activation in T Lymphocytes

We report that stromal cell–derived factor (SDF)-1 has the remarkable capacity to induce sustained signaling through CXC chemokine receptor 4 (CXCR4). In contrast to other chemokines, such as monocyte chemotactic protein 1 (CC chemokine receptor 2 [CCR2]), macrophage inflammatory protein 1β (CCR5),...

Descripción completa

Detalles Bibliográficos
Autores principales: Tilton, Bettina, Ho, Liza, Oberlin, Estelle, Loetscher, Pius, Baleux, Françoise, Clark-Lewis, Ian, Thelen, Marcus
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193218/
https://www.ncbi.nlm.nih.gov/pubmed/10934220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193218/
https://www.ncbi.nlm.nih.gov/pubmed/10934220

Ejemplares similares