Cargando…

Differential Influence on Cytotoxic T Lymphocyte Epitope Presentation by Controlled Expression of Either Proteasome Immunosubunits or Pa28

The proteasome is the principal provider of major histocompatibility complex (MHC) class I–presented peptides. Interferon (IFN)-γ induces expression of three catalytically active proteasome subunits (LMP2, LMP7, and MECL-1) and the proteasome-associated activator PA28. These molecules are thought to...

Descripción completa

Detalles Bibliográficos
Autores principales: van Hall, Thorbald, Sijts, Alice, Camps, Marcel, Offringa, Rienk, Melief, Cornelis, Kloetzel, Peter-M., Ossendorp, Ferry
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193234/
https://www.ncbi.nlm.nih.gov/pubmed/10952718