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Homeostasis-Stimulated Proliferation Drives Naive T Cells to Differentiate Directly into Memory T Cells

The developmental requirements for immunological memory, a central feature of adaptive immune responses, is largely obscure. We show that as naive CD8 T cells undergo homeostasis-driven proliferation in lymphopenic mice in the absence of overt antigenic stimulation, they progressively acquire phenot...

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Detalles Bibliográficos
Autores principales: Cho, Bryan K., Rao, Varada P., Ge, Qing, Eisen, Herman N., Chen, Jianzhu
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193235/
https://www.ncbi.nlm.nih.gov/pubmed/10952724