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Perforin-Mediated Cytotoxicity Is Critical for Surveillance of Spontaneous Lymphoma

Immune surveillance by cytotoxic lymphocytes against cancer has been postulated for decades, but direct evidence for the role of cytotoxic lymphocytes in protecting against spontaneous malignancy has been lacking. As the rejection of many experimental cancers by cytotoxic T lymphocytes and natural k...

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Detalles Bibliográficos
Autores principales: Smyth, Mark J., Thia, Kevin Y.T., Street, Shayna E.A., MacGregor, Duncan, Godfrey, Dale I., Trapani, Joseph A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193269/
https://www.ncbi.nlm.nih.gov/pubmed/10974040