Inhibition of E-Selectin Gene Expression by Transforming Growth Factor β in Endothelial Cells Involves Coactivator Integration of Smad and Nuclear Factor κB–Mediated Signals

Transforming growth factor (TGF)-β(1) is a pleiotropic cytokine/growth factor that is thought to play a critical role in the modulation of inflammatory events. We demonstrate that exogenous TGF-β(1) can inhibit the expression of the proinflammatory adhesion molecule, E-selectin, in vascular endothel...

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Detalles Bibliográficos
Autores principales: DiChiara, Maria R., Kiely, Jeanne Marie, Gimbrone, Michael A., Lee, Mu-En, Perrella, Mark A., Topper, James N.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193275/
https://www.ncbi.nlm.nih.gov/pubmed/10974035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193275/
https://www.ncbi.nlm.nih.gov/pubmed/10974035

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