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Regulation of Elastinolytic Cysteine Proteinase Activity in Normal and Cathepsin K–Deficient Human Macrophages

Human macrophages mediate the dissolution of elastic lamina by mobilizing tissue-destructive cysteine proteinases. While macrophage-mediated elastin degradation has been linked to the expression of cathepsins L and S, these cells also express cathepsin K, a new member of the cysteine proteinase fami...

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Detalles Bibliográficos
Autores principales: Punturieri, Antonello, Filippov, Sergey, Allen, Edward, Caras, Ingrid, Murray, Richard, Reddy, Vivek, Weiss, Stephen J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193285/
https://www.ncbi.nlm.nih.gov/pubmed/10993910