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A Transcription Function for the T Cell–Specific Adapter (Tsad) Protein in T Cells: Critical Role of the Tsad Src Homology 2 Domain

T cell–specific adapter (TSAd) protein is an Src homology 2 (SH2) domain–containing adapter molecule implicated in T cell receptor for antigen (TCR)-mediated interleukin 2 (IL-2) secretion in T cells. Here, we demonstrate that a substantial fraction of TSAd is found in the T cell nucleus. Nuclear im...

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Detalles Bibliográficos
Autores principales: Marti, Francesc, Post, Nicholas H., Chan, Elena, King, Philip D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193301/
https://www.ncbi.nlm.nih.gov/pubmed/11413197