An Alternative Open Reading Frame of the Human Macrophage Colony-Stimulating Factor Gene Is Independently Translated and Codes for an Antigenic Peptide of 14 Amino Acids Recognized by Tumor-Infiltrating Cd8 T Lymphocytes

We show that cytotoxic T lymphocytes (CTLs) infiltrating a kidney tumor recognize a peptide encoded by an alternative open reading frame (ORF) of the macrophage colony-stimulating factor (M-CSF) gene. Remarkably, this alternative ORF, which is translated in many tumors concurrently with the major OR...

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Detalles Bibliográficos
Autores principales: Probst-Kepper, Michael, Stroobant, Vincent, Kridel, Robert, Gaugler, Béatrice, Landry, Claire, Brasseur, Francis, Cosyns, Jean-Pierre, Weynand, Birgit, Boon, Thierry, Van den Eynde, Benoit J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193327/
https://www.ncbi.nlm.nih.gov/pubmed/11369790

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193327/
https://www.ncbi.nlm.nih.gov/pubmed/11369790

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