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T Cell Recognition of the Dominant I-A(k)–Restricted Hen Egg Lysozyme Epitope: Critical Role for Asparagine Deamidation
Type-B T cells raised against the immunodominant peptide in hen egg lysozyme (HEL(48–62)) do not respond to whole lysozyme, and this has been thought to indicate that peptide can bind to l-A(k) in different conformations. Here we demonstrate that such T cells recognize a deamidated form of the HEL p...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193382/ https://www.ncbi.nlm.nih.gov/pubmed/11390431 |