Identification of a Crucial Energetic Footprint on the α1 Helix of Human Histocompatibility Leukocyte Antigen (Hla)-A2 That Provides Functional Interactions for Recognition by Tax Peptide/Hla-A2–Specific T Cell Receptors

Structural studies have shown that class I major histocompatibility complex (MHC)-restricted peptide-specific T cell receptor (TCR)-α/βs make multiple contacts with the α1 and α2 helices of the MHC, but it is unclear which or how many of these interactions contribute to functional binding. We have a...

Descripción completa

Detalles Bibliográficos
Autores principales: Baker, Brian M., Turner, Richard V., Gagnon, Susan J., Wiley, Don C., Biddison, William E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193388/
https://www.ncbi.nlm.nih.gov/pubmed/11238586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193388/
https://www.ncbi.nlm.nih.gov/pubmed/11238586

Ejemplares similares