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An Instructive Component in T Helper Cell Type 2 (Th2) Development Mediated by Gata-3

Although interleukin (IL)-12 and IL-4 polarize naive CD4(+) T cells toward T helper cell type 1 (Th1) or Th2 phenotypes, it is not known whether cytokines instruct the developmental fate in uncommitted progenitors or select for outgrowth of cells that have stochastically committed to a particular fa...

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Detalles Bibliográficos
Autores principales: Farrar, J. David, Ouyang, Wenjun, Löhning, Max, Assenmacher, Mario, Radbruch, Andreas, Kanagawa, Osami, Murphy, Kenneth M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193395/
https://www.ncbi.nlm.nih.gov/pubmed/11238595