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Pivotal Role of Signal Transducer and Activator of Transcription (Stat)4 and Stat6 in the Innate Immune Response during Sepsis

Signal transducer and activator of transcription (Stat)4 and Stat6 are transcription factors that provide type 1 and type 2 response, respectively. Here, we explored the role of Stat4 and Stat6 in innate immunity during septic peritonitis. Stat4(−/)− and Stat6(−/)− mice were resistant to the lethali...

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Detalles Bibliográficos
Autores principales: Matsukawa, Akihiro, Kaplan, Mark H., Hogaboam, Cory M., Lukacs, Nicholas W., Kunkel, Steven L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193416/
https://www.ncbi.nlm.nih.gov/pubmed/11257135