Conditional Vascular Cell Adhesion Molecule 1 Deletion in Mice: Impaired Lymphocyte Migration to Bone Marrow

We generated vascular cell adhesion molecule (VCAM)-1 “knock-in” mice and Cre recombinase transgenic mice to delete the VCAM-1 gene (vcam-1) in whole mice, thereby overcoming the embryonic lethality seen with conventional vcam-1–deficient mice. vcam-1 knock-in mice expressed normal levels of VCAM-1...

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Detalles Bibliográficos
Autores principales: Koni, Pandelakis A., Joshi, Sunil K., Temann, Ulla-Angela, Olson, Dian, Burkly, Linda, Flavell, Richard A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193418/
https://www.ncbi.nlm.nih.gov/pubmed/11257140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193418/
https://www.ncbi.nlm.nih.gov/pubmed/11257140

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