Constitutively Activated Akt-1 Is Vital for the Survival of Human Monocyte-Differentiated Macrophages: Role of Mcl-1, Independent of Nuclear Factor (Nf)-κb, Bad, or Caspase Activation

Recent data from mice deficient for phosphatase and tensin homologue deleted from chromosome 10 or src homology 2 domain–containing 5′ inositol phosphatase, phosphatases that negatively regulate the phosphatidylinositol 3-kinase (PI3K) pathway, revealed an increased number of macrophages in these an...

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Detalles Bibliográficos
Autores principales: Liu, Hongtao, Perlman, Harris, Pagliari, Lisa J., Pope, Richard M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193455/
https://www.ncbi.nlm.nih.gov/pubmed/11457886

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193455/
https://www.ncbi.nlm.nih.gov/pubmed/11457886

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