Regulation of Interleukin (Il)-18 Receptor α Chain Expression on Cd4(+) T Cells during T Helper (Th)1/Th2 Differentiation: Critical Downregulatory Role of IL-4

Interleukin (IL)-18 has been well characterized as a costimulatory factor for the induction of IL-12–mediated interferon (IFN)-γ production by T helper (Th)1 cells, but also can induce IL-4 production and thus facilitate the differentiation of Th2 cells. To determine the mechanisms by which IL-18 mi...

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Detalles Bibliográficos
Autores principales: Smeltz, Ronald B., Chen, June, Hu-Li, Jane, Shevach, Ethan M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193456/
https://www.ncbi.nlm.nih.gov/pubmed/11457889

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193456/
https://www.ncbi.nlm.nih.gov/pubmed/11457889

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