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Regulation of Interleukin (Il)-18 Receptor α Chain Expression on Cd4(+) T Cells during T Helper (Th)1/Th2 Differentiation: Critical Downregulatory Role of IL-4
Interleukin (IL)-18 has been well characterized as a costimulatory factor for the induction of IL-12–mediated interferon (IFN)-γ production by T helper (Th)1 cells, but also can induce IL-4 production and thus facilitate the differentiation of Th2 cells. To determine the mechanisms by which IL-18 mi...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2001
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193456/ https://www.ncbi.nlm.nih.gov/pubmed/11457889 |