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Deficiency of Small Gtpase Rac2 Affects T Cell Activation
Rac2 is a hematopoietic-specific GTPase acting as a molecular switch to mediate both transcriptional activation and cell morphological changes. We have examined the effect of Rac2 deficiency during T cell activation. In Rac2(−/−) T cells, proliferation was reduced upon stimulation with either plate-...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193485/ https://www.ncbi.nlm.nih.gov/pubmed/11581314 |