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Notch 1–Deficient Common Lymphoid Precursors Adopt a B Cell Fate in the Thymus

We have recently reported that Notch 1, a member of the Notch multigene family, is essential for the development of murine T cells. Using a mouse model in which Notch 1 is inactivated in bone marrow (BM) precursors we have shown that B cells instead of T cells are found in the thymus of BM chimeras....

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Detalles Bibliográficos
Autores principales: Wilson, Anne, MacDonald, H. Robson, Radtke, Freddy
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193487/
https://www.ncbi.nlm.nih.gov/pubmed/11581321