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Notch 1–Deficient Common Lymphoid Precursors Adopt a B Cell Fate in the Thymus
We have recently reported that Notch 1, a member of the Notch multigene family, is essential for the development of murine T cells. Using a mouse model in which Notch 1 is inactivated in bone marrow (BM) precursors we have shown that B cells instead of T cells are found in the thymus of BM chimeras....
Autores principales: | Wilson, Anne, MacDonald, H. Robson, Radtke, Freddy |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193487/ https://www.ncbi.nlm.nih.gov/pubmed/11581321 |
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