The Role of Recombination Activating Gene (RAG) Reinduction in Thymocyte Development in Vivo

Assembly of T cell receptor (TCR)α/β genes by variable/diversity/joining (V[D]J) rearrangement is an ordered process beginning with recombination activating gene (RAG) expression and TCRβ recombination in CD4(−)CD8(−)CD25(+) thymocytes. In these cells, TCRβ expression leads to clonal expansion, RAG...

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Detalles Bibliográficos
Autores principales: Yannoutsos, Nikos, Wilson, Patrick, Yu, Wong, Chen, Hua Tang, Nussenzweig, Andre, Petrie, Howard, Nussenzweig, Michel C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193494/
https://www.ncbi.nlm.nih.gov/pubmed/11514603

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193494/
https://www.ncbi.nlm.nih.gov/pubmed/11514603

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