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Major Histocompatibility Complex Class II–Positive Cortical Epithelium Mediates the Selection of Cd4(+)25(+) Immunoregulatory T Cells

CD4(+)25(+) T cells are a unique population of immunoregulatory T cells which are critical for the prevention of autoimmunity. To address the thymic selection of these cells we have used two models of attenuated thymic deletion. In K14-A(β) (b) mice, major histocompatibility complex (MHC) class II I...

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Detalles Bibliográficos
Autores principales: Bensinger, Steven J., Bandeira, Antonio, Jordan, Martha S., Caton, Andrew J., Laufer, Terri M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193499/
https://www.ncbi.nlm.nih.gov/pubmed/11514600