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Cd47 (Integrin-Associated Protein) Engagement of Dendritic Cell and Macrophage Counterreceptors Is Required to Prevent the Clearance of Donor Lymphohematopoietic Cells

Integrin-associated protein (CD47) is a broadly expressed protein that costimulates T cells, facilitates leukocyte migration, and inhibits macrophage scavenger function. To determine the role of CD47 in regulating alloresponses, CD47(+/+) or CD47(−/−) T cells were infused into irradiated or noncondi...

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Detalles Bibliográficos
Autores principales: Blazar, Bruce R., Lindberg, Frederik P., Ingulli, Elizabeth, Panoskaltsis-Mortari, Angela, Oldenborg, Per-Arne, Iizuka, Koho, Yokoyama, Wayne M., Taylor, Patricia A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193501/
https://www.ncbi.nlm.nih.gov/pubmed/11514609