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Identification of the Transferrin Receptor as a Novel Immunoglobulin (Ig)a1 Receptor and Its Enhanced Expression on Mesangial Cells in Iga Nephropathy

The biological functions of immunoglobulin (Ig)A antibodies depend primarily on their interaction with cell surface receptors. Four IgA receptors are presently characterized. The FcαRI (CD89) expressed by myeloid cells selectively binds IgA1 and IgA2 antibodies, whereas the poly-IgR, Fcα/μR, and asi...

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Detalles Bibliográficos
Autores principales: Moura, Ivan C., Centelles, Miguel N., Arcos-Fajardo, Michelle, Malheiros, Denise M., Collawn, James F., Cooper, Max D., Monteiro, Renato C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193503/
https://www.ncbi.nlm.nih.gov/pubmed/11514599